Fully-automated deep learning slice-based muscle estimation from CT
images for sarcopenia assessment
- URL: http://arxiv.org/abs/2006.06432v1
- Date: Wed, 10 Jun 2020 12:05:55 GMT
- Title: Fully-automated deep learning slice-based muscle estimation from CT
images for sarcopenia assessment
- Authors: Fahdi Kanavati, Shah Islam, Zohaib Arain, Eric O. Aboagye, Andrea
Rockall
- Abstract summary: This retrospective study was conducted using a collection of public and privately available CT images.
The method consisted of two stages: slice detection from a CT volume and single-slice CT segmentation.
The output consisted of a segmented muscle mass on a CT slice at the level of L3 vertebra.
- Score: 0.10499611180329801
- License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
- Abstract: Objective: To demonstrate the effectiveness of using a deep learning-based
approach for a fully automated slice-based measurement of muscle mass for
assessing sarcopenia on CT scans of the abdomen without any case exclusion
criteria.
Materials and Methods: This retrospective study was conducted using a
collection of public and privately available CT images (n = 1070). The method
consisted of two stages: slice detection from a CT volume and single-slice CT
segmentation. Both stages used Fully Convolutional Neural Networks (FCNN) and
were based on a UNet-like architecture. Input data consisted of CT volumes with
a variety of fields of view. The output consisted of a segmented muscle mass on
a CT slice at the level of L3 vertebra. The muscle mass is segmented into
erector spinae, psoas, and rectus abdominus muscle groups. The output was
tested against manual ground-truth segmentation by an expert annotator.
Results: 3-fold cross validation was used to evaluate the proposed method.
The slice detection cross validation error was 1.41+-5.02 (in slices). The
segmentation cross validation Dice overlaps were 0.97+-0.02, 0.95+-0.04,
0.94+-0.04 for erector spinae, psoas, and rectus abdominus, respectively, and
0.96+-0.02 for the combined muscle mass.
Conclusion: A deep learning approach to detect CT slices and segment muscle
mass to perform slice-based analysis of sarcopenia is an effective and
promising approach. The use of FCNN to accurately and efficiently detect a
slice in CT volumes with a variety of fields of view, occlusions, and slice
thicknesses was demonstrated.
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