Joint Optimization of Hadamard Sensing and Reconstruction in Compressed
Sensing Fluorescence Microscopy
- URL: http://arxiv.org/abs/2105.07961v1
- Date: Mon, 17 May 2021 15:42:28 GMT
- Title: Joint Optimization of Hadamard Sensing and Reconstruction in Compressed
Sensing Fluorescence Microscopy
- Authors: Alan Q. Wang, Aaron K. LaViolette, Leo Moon, Chris Xu, and Mert R.
Sabuncu
- Abstract summary: We propose a method of jointly optimizing both sensing and reconstruction end-to-end under a total measurement constraint.
We train our model on a rich dataset of confocal, two-photon, and wide-field microscopy images.
- Score: 9.210673747947165
- License: http://creativecommons.org/licenses/by/4.0/
- Abstract: Compressed sensing fluorescence microscopy (CS-FM) proposes a scheme whereby
less measurements are collected during sensing and reconstruction is performed
to recover the image. Much work has gone into optimizing the sensing and
reconstruction portions separately. We propose a method of jointly optimizing
both sensing and reconstruction end-to-end under a total measurement
constraint, enabling learning of the optimal sensing scheme concurrently with
the parameters of a neural network-based reconstruction network. We train our
model on a rich dataset of confocal, two-photon, and wide-field microscopy
images comprising of a variety of biological samples. We show that our method
outperforms several baseline sensing schemes and a regularized regression
reconstruction algorithm.
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