Self-transfer learning via patches: A prostate cancer triage approach based on bi-parametric MRI

• URL: http://arxiv.org/abs/2107.10806v1
• Date: Thu, 22 Jul 2021 17:02:38 GMT
• Title: Self-transfer learning via patches: A prostate cancer triage approach based on bi-parametric MRI
• Authors: Alvaro Fernandez-Quilez, Trygve Eftest{\o}l, Morten Goodwin, Svein Reidar Kjosavik, Ketil Oppedal
• Abstract summary: Prostate cancer (PCa) is the second most common cancer diagnosed among men worldwide. The current PCa diagnostic pathway comes at the cost of substantial overdiagnosis, leading to unnecessary treatment and further testing. We present a patch-based pre-training strategy to distinguish between clinically significant (cS) and non-clinically significant (ncS) lesions.
• Score: 1.3934382972253603
• License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
• Abstract: Prostate cancer (PCa) is the second most common cancer diagnosed among men worldwide. The current PCa diagnostic pathway comes at the cost of substantial overdiagnosis, leading to unnecessary treatment and further testing. Bi-parametric magnetic resonance imaging (bp-MRI) based on apparent diffusion coefficient maps (ADC) and T2-weighted (T2w) sequences has been proposed as a triage test to differentiate between clinically significant (cS) and non-clinically significant (ncS) prostate lesions. However, analysis of the sequences relies on expertise, requires specialized training, and suffers from inter-observer variability. Deep learning (DL) techniques hold promise in tasks such as classification and detection. Nevertheless, they rely on large amounts of annotated data which is not common in the medical field. In order to palliate such issues, existing works rely on transfer learning (TL) and ImageNet pre-training, which has been proven to be sub-optimal for the medical imaging domain. In this paper, we present a patch-based pre-training strategy to distinguish between cS and ncS lesions which exploit the region of interest (ROI) of the patched source domain to efficiently train a classifier in the full-slice target domain which does not require annotations by making use of transfer learning (TL). We provide a comprehensive comparison between several CNNs architectures and different settings which are presented as a baseline. Moreover, we explore cross-domain TL which exploits both MRI modalities and improves single modality results. Finally, we show how our approaches outperform the standard approaches by a considerable margin

Related papers

• Enhancing Prostate Cancer Diagnosis with Deep Learning: A Study using mpMRI Segmentation and Classification [0.0]
  Prostate cancer (PCa) is a severe disease among men globally. It is important to identify PCa early and make a precise diagnosis for effective treatment. Deep learning (DL) models can enhance existing clinical systems and improve patient care by locating regions of interest for physicians. This work uses well-known DL models for the classification and segmentation of mpMRI images to detect PCa.
  arXiv  Detail & Related papers  (2023-10-09T03:00:15Z)
• Radiomics Boosts Deep Learning Model for IPMN Classification [3.4659499358648675]
  Intraductal Papillary Mucinous Neoplasm (IPMN) cysts are pre-malignant pancreas lesions, and they can progress into pancreatic cancer. In this study, we propose a novel computer-aided diagnosis pipeline for IPMN risk classification from MRI scans.
  arXiv  Detail & Related papers  (2023-09-11T22:41:52Z)
• Improving Multiple Sclerosis Lesion Segmentation Across Clinical Sites: A Federated Learning Approach with Noise-Resilient Training [75.40980802817349]
  Deep learning models have shown promise for automatically segmenting MS lesions, but the scarcity of accurately annotated data hinders progress in this area. We introduce a Decoupled Hard Label Correction (DHLC) strategy that considers the imbalanced distribution and fuzzy boundaries of MS lesions. We also introduce a Centrally Enhanced Label Correction (CELC) strategy, which leverages the aggregated central model as a correction teacher for all sites.
  arXiv  Detail & Related papers  (2023-08-31T00:36:10Z)
• Domain Transfer Through Image-to-Image Translation for Uncertainty-Aware Prostate Cancer Classification [42.75911994044675]
  We present a novel approach for unpaired image-to-image translation of prostate MRIs and an uncertainty-aware training approach for classifying clinically significant PCa. Our approach involves a novel pipeline for translating unpaired 3.0T multi-parametric prostate MRIs to 1.5T, thereby augmenting the available training data. Our experiments demonstrate that the proposed method significantly improves the Area Under ROC Curve (AUC) by over 20% compared to the previous work.
  arXiv  Detail & Related papers  (2023-07-02T05:26:54Z)
• Rethinking Semi-Supervised Medical Image Segmentation: A Variance-Reduction Perspective [51.70661197256033]
  We propose ARCO, a semi-supervised contrastive learning framework with stratified group theory for medical image segmentation. We first propose building ARCO through the concept of variance-reduced estimation and show that certain variance-reduction techniques are particularly beneficial in pixel/voxel-level segmentation tasks. We experimentally validate our approaches on eight benchmarks, i.e., five 2D/3D medical and three semantic segmentation datasets, with different label settings.
  arXiv  Detail & Related papers  (2023-02-03T13:50:25Z)
• End-to-end Learning for Image-based Detection of Molecular Alterations in Digital Pathology [1.916179040410189]
  Current approaches for classification of whole slide images (WSI) in digital pathology predominantly utilize a two-stage learning pipeline. A major drawback of such approaches is the requirement for task-specific auxiliary labels which are not acquired in clinical routine. We propose a novel learning pipeline for WSI classification that is trainable end-to-end and does not require any auxiliary annotations.
  arXiv  Detail & Related papers  (2022-06-30T20:30:33Z)
• The Brain Tumor Sequence Registration (BraTS-Reg) Challenge: Establishing Correspondence Between Pre-Operative and Follow-up MRI Scans of Diffuse Glioma Patients [31.567542945171834]
  We describe the Brain Tumor Sequence Registration (BraTS-Reg) challenge. BraTS-Reg is the first public benchmark environment for deformable registration algorithms. The aim of BraTS-Reg is to continue to serve as an active resource for research.
  arXiv  Detail & Related papers  (2021-12-13T19:25:16Z)
• Cross-Site Severity Assessment of COVID-19 from CT Images via Domain Adaptation [64.59521853145368]
  Early and accurate severity assessment of Coronavirus disease 2019 (COVID-19) based on computed tomography (CT) images offers a great help to the estimation of intensive care unit event. To augment the labeled data and improve the generalization ability of the classification model, it is necessary to aggregate data from multiple sites. This task faces several challenges including class imbalance between mild and severe infections, domain distribution discrepancy between sites, and presence of heterogeneous features.
  arXiv  Detail & Related papers  (2021-09-08T07:56:51Z)
• Cross-Modality Brain Tumor Segmentation via Bidirectional Global-to-Local Unsupervised Domain Adaptation [61.01704175938995]
  In this paper, we propose a novel Bidirectional Global-to-Local (BiGL) adaptation framework under a UDA scheme. Specifically, a bidirectional image synthesis and segmentation module is proposed to segment the brain tumor. The proposed method outperforms several state-of-the-art unsupervised domain adaptation methods by a large margin.
  arXiv  Detail & Related papers  (2021-05-17T10:11:45Z)
• Detecting Pancreatic Ductal Adenocarcinoma in Multi-phase CT Scans via Alignment Ensemble [77.5625174267105]
  Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers among the population. Multiple phases provide more information than single phase, but they are unaligned and inhomogeneous in texture. We suggest an ensemble of all these alignments as a promising way to boost the performance of PDAC detection.
  arXiv  Detail & Related papers  (2020-03-18T19:06:27Z)
• MS-Net: Multi-Site Network for Improving Prostate Segmentation with Heterogeneous MRI Data [75.73881040581767]
  We propose a novel multi-site network (MS-Net) for improving prostate segmentation by learning robust representations. Our MS-Net improves the performance across all datasets consistently, and outperforms state-of-the-art methods for multi-site learning.
  arXiv  Detail & Related papers  (2020-02-09T14:11:50Z)

This list is automatically generated from the titles and abstracts of the papers in this site.

This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.