PhysioMTL: Personalizing Physiological Patterns using Optimal Transport
Multi-Task Regression
- URL: http://arxiv.org/abs/2203.12595v1
- Date: Sat, 19 Mar 2022 19:14:25 GMT
- Title: PhysioMTL: Personalizing Physiological Patterns using Optimal Transport
Multi-Task Regression
- Authors: Jiacheng Zhu, Gregory Darnell, Agni Kumar, Ding Zhao, Bo Li, Xuanlong
Nguyen, Shirley You Ren
- Abstract summary: Heart rate variability (HRV) is a practical and noninvasive measure of autonomic nervous system activity.
We develop Physiological Multitask-Learning (PhysioMTL) by harnessing Optimal Transport theory within a Multitask-learning framework.
- Score: 21.254400561280296
- License: http://creativecommons.org/licenses/by/4.0/
- Abstract: Heart rate variability (HRV) is a practical and noninvasive measure of
autonomic nervous system activity, which plays an essential role in
cardiovascular health. However, using HRV to assess physiology status is
challenging. Even in clinical settings, HRV is sensitive to acute stressors
such as physical activity, mental stress, hydration, alcohol, and sleep.
Wearable devices provide convenient HRV measurements, but the irregularity of
measurements and uncaptured stressors can bias conventional analytical methods.
To better interpret HRV measurements for downstream healthcare applications, we
learn a personalized diurnal rhythm as an accurate physiological indicator for
each individual. We develop Physiological Multitask-Learning (PhysioMTL) by
harnessing Optimal Transport theory within a Multitask-learning (MTL)
framework. The proposed method learns an individual-specific predictive model
from heterogeneous observations, and enables estimation of an optimal transport
map that yields a push forward operation onto the demographic features for each
task. Our model outperforms competing MTL methodologies on unobserved
predictive tasks for synthetic and two real-world datasets. Specifically, our
method provides remarkable prediction results on unseen held-out subjects given
only $20\%$ of the subjects in real-world observational studies. Furthermore,
our model enables a counterfactual engine that generates the effect of acute
stressors and chronic conditions on HRV rhythms.
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