Parameter Inference via Differentiable Diffusion Bridge Importance Sampling
- URL: http://arxiv.org/abs/2411.08993v1
- Date: Wed, 13 Nov 2024 19:33:47 GMT
- Title: Parameter Inference via Differentiable Diffusion Bridge Importance Sampling
- Authors: Nicklas Boserup, Gefan Yang, Michael Lind Severinsen, Christy Anna Hipsley, Stefan Sommer,
- Abstract summary: We introduce a methodology for performing parameter inference in high-dimensional, non-linear diffusion processes.
We illustrate its applicability for obtaining insights into the evolution of and relationships between species, including ancestral state reconstruction.
This novel, numerically stable, score matching-based parameter inference framework is presented and demonstrated on biological two- and three-dimensional morphometry data.
- Score: 1.747623282473278
- License:
- Abstract: We introduce a methodology for performing parameter inference in high-dimensional, non-linear diffusion processes. We illustrate its applicability for obtaining insights into the evolution of and relationships between species, including ancestral state reconstruction. Estimation is performed by utilising score matching to approximate diffusion bridges, which are subsequently used in an importance sampler to estimate log-likelihoods. The entire setup is differentiable, allowing gradient ascent on approximated log-likelihoods. This allows both parameter inference and diffusion mean estimation. This novel, numerically stable, score matching-based parameter inference framework is presented and demonstrated on biological two- and three-dimensional morphometry data.
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