CXR-LT 2024: A MICCAI challenge on long-tailed, multi-label, and zero-shot disease classification from chest X-ray

• URL: http://arxiv.org/abs/2506.07984v1
• Date: Mon, 09 Jun 2025 17:53:31 GMT
• Title: CXR-LT 2024: A MICCAI challenge on long-tailed, multi-label, and zero-shot disease classification from chest X-ray
• Authors: Mingquan Lin, Gregory Holste, Song Wang, Yiliang Zhou, Yishu Wei, Imon Banerjee, Pengyi Chen, Tianjie Dai, Yuexi Du, Nicha C. Dvornek, Yuyan Ge, Zuowei Guo, Shouhei Hanaoka, Dongkyun Kim, Pablo Messina, Yang Lu, Denis Parra, Donghyun Son, Álvaro Soto, Aisha Urooj, René Vidal, Yosuke Yamagishi, Zefan Yang, Ruichi Zhang, Yang Zhou, Leo Anthony Celi, Ronald M. Summers, Zhiyong Lu, Hao Chen, Adam Flanders, George Shih, Zhangyang Wang, Yifan Peng,
• Abstract summary: The CXR-LT series is a community-driven initiative designed to enhance lung disease classification using chest X-rays.<n>The CXR-LT 2024 expands the dataset to 377,110 chest X-rays (CXRs) and 45 disease labels, including 19 new rare disease findings.<n>This paper provides an overview of CXR-LT 2024, detailing the data curation process and consolidating state-of-the-art solutions.
• Score: 64.2434525370243
• License: http://creativecommons.org/licenses/by/4.0/
• Abstract: The CXR-LT series is a community-driven initiative designed to enhance lung disease classification using chest X-rays (CXR). It tackles challenges in open long-tailed lung disease classification and enhances the measurability of state-of-the-art techniques. The first event, CXR-LT 2023, aimed to achieve these goals by providing high-quality benchmark CXR data for model development and conducting comprehensive evaluations to identify ongoing issues impacting lung disease classification performance. Building on the success of CXR-LT 2023, the CXR-LT 2024 expands the dataset to 377,110 chest X-rays (CXRs) and 45 disease labels, including 19 new rare disease findings. It also introduces a new focus on zero-shot learning to address limitations identified in the previous event. Specifically, CXR-LT 2024 features three tasks: (i) long-tailed classification on a large, noisy test set, (ii) long-tailed classification on a manually annotated "gold standard" subset, and (iii) zero-shot generalization to five previously unseen disease findings. This paper provides an overview of CXR-LT 2024, detailing the data curation process and consolidating state-of-the-art solutions, including the use of multimodal models for rare disease detection, advanced generative approaches to handle noisy labels, and zero-shot learning strategies for unseen diseases. Additionally, the expanded dataset enhances disease coverage to better represent real-world clinical settings, offering a valuable resource for future research. By synthesizing the insights and innovations of participating teams, we aim to advance the development of clinically realistic and generalizable diagnostic models for chest radiography.

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