Assessing gender fairness in EEG-based machine learning detection of Parkinson's disease: A multi-center study

• URL: http://arxiv.org/abs/2303.06376v1
• Date: Sat, 11 Mar 2023 10:57:23 GMT
• Title: Assessing gender fairness in EEG-based machine learning detection of Parkinson's disease: A multi-center study
• Authors: Anna Kurbatskaya, Alberto Jaramillo-Jimenez, John Fredy Ochoa-Gomez, Kolbj{\o}rn Br{\o}nnick, Alvaro Fernandez-Quilez
• Abstract summary: We perform a systematic analysis of the detection ability for gender sub-groups in a multi-center setting of a previously developed ML algorithm. We find significant differences in the PD detection ability for males and females at testing time. We find significantly higher activity for a set of parietal and frontal EEG channels and frequency sub-bands for PD and non-PD males that might explain the differences in the PD detection ability for the gender sub-groups.
• Score: 0.125828876338076
• License: http://creativecommons.org/licenses/by/4.0/
• Abstract: As the number of automatic tools based on machine learning (ML) and resting-state electroencephalography (rs-EEG) for Parkinson's disease (PD) detection keeps growing, the assessment of possible exacerbation of health disparities by means of fairness and bias analysis becomes more relevant. Protected attributes, such as gender, play an important role in PD diagnosis development. However, analysis of sub-group populations stemming from different genders is seldom taken into consideration in ML models' development or the performance assessment for PD detection. In this work, we perform a systematic analysis of the detection ability for gender sub-groups in a multi-center setting of a previously developed ML algorithm based on power spectral density (PSD) features of rs-EEG. We find significant differences in the PD detection ability for males and females at testing time (80.5% vs. 63.7% accuracy) and significantly higher activity for a set of parietal and frontal EEG channels and frequency sub-bands for PD and non-PD males that might explain the differences in the PD detection ability for the gender sub-groups.

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