Feasibility Study of a Diffusion-Based Model for Cross-Modal Generation of Knee MRI from X-ray: Integrating Radiographic Feature Information

• URL: http://arxiv.org/abs/2410.06997v3
• Date: Fri, 27 Dec 2024 06:00:28 GMT
• Title: Feasibility Study of a Diffusion-Based Model for Cross-Modal Generation of Knee MRI from X-ray: Integrating Radiographic Feature Information
• Authors: Zhe Wang, Yung Hsin Chen, Aladine Chetouani, Fabian Bauer, Yuhua Ru, Fang Chen, Liping Zhang, Rachid Jennane, Mohamed Jarraya,
• Abstract summary: Knee osteoarthritis (KOA) is a prevalent musculoskeletal disorder, often diagnosed using X-rays due to its cost-effectiveness.<n>Magnetic Resonance Imaging (MRI) provides superior soft tissue visualization and serves as a valuable supplementary diagnostic tool.
• Score: 8.466319668322432
• License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
• Abstract: Knee osteoarthritis (KOA) is a prevalent musculoskeletal disorder, often diagnosed using X-rays due to its cost-effectiveness. While Magnetic Resonance Imaging (MRI) provides superior soft tissue visualization and serves as a valuable supplementary diagnostic tool, its high cost and limited accessibility significantly restrict its widespread use. To explore the feasibility of bridging this imaging gap, we conducted a feasibility study leveraging a diffusion-based model that uses an X-ray image as conditional input, alongside target depth and additional patient-specific feature information, to generate corresponding MRI sequences. Our findings demonstrate that the MRI volumes generated by our approach is visually closer to real MRI scans. Moreover, increasing inference steps enhances the continuity and smoothness of the synthesized MRI sequences. Through ablation studies, we further validate that integrating supplementary patient-specific information, beyond what X-rays alone can provide, enhances the accuracy and clinical relevance of the generated MRI, which underscores the potential of leveraging external patient-specific information to improve the MRI generation. This study is available at https://zwang78.github.io/.

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