Interpretable Deep Transfer Learning for Breast Ultrasound Cancer Detection: A Multi-Dataset Study

• URL: http://arxiv.org/abs/2509.05004v1
• Date: Fri, 05 Sep 2025 11:03:15 GMT
• Title: Interpretable Deep Transfer Learning for Breast Ultrasound Cancer Detection: A Multi-Dataset Study
• Authors: Mohammad Abbadi, Yassine Himeur, Shadi Atalla, Wathiq Mansoor,
• Abstract summary: This paper presents the application of machine learning and deep learning techniques for breast cancer classification using ultrasound images.<n>We evaluate classical machine learning models (SVM, KNN) and deep convolutional neural networks (ResNet-18, EfficientNet-B0, GoogLeNet)<n>ResNet-18 achieves the highest accuracy (99.7%) and perfect sensitivity for malignant lesions.
• Score: 3.8015258892590924
• License: http://creativecommons.org/licenses/by/4.0/
• Abstract: Breast cancer remains a leading cause of cancer-related mortality among women worldwide. Ultrasound imaging, widely used due to its safety and cost-effectiveness, plays a key role in early detection, especially in patients with dense breast tissue. This paper presents a comprehensive study on the application of machine learning and deep learning techniques for breast cancer classification using ultrasound images. Using datasets such as BUSI, BUS-BRA, and BrEaST-Lesions USG, we evaluate classical machine learning models (SVM, KNN) and deep convolutional neural networks (ResNet-18, EfficientNet-B0, GoogLeNet). Experimental results show that ResNet-18 achieves the highest accuracy (99.7%) and perfect sensitivity for malignant lesions. Classical ML models, though outperformed by CNNs, achieve competitive performance when enhanced with deep feature extraction. Grad-CAM visualizations further improve model transparency by highlighting diagnostically relevant image regions. These findings support the integration of AI-based diagnostic tools into clinical workflows and demonstrate the feasibility of deploying high-performing, interpretable systems for ultrasound-based breast cancer detection.

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