TraceCoder: Towards Traceable ICD Coding via Multi-Source Knowledge Integration
- URL: http://arxiv.org/abs/2510.15267v1
- Date: Fri, 17 Oct 2025 03:08:07 GMT
- Title: TraceCoder: Towards Traceable ICD Coding via Multi-Source Knowledge Integration
- Authors: Mucheng Ren, He Chen, Yuchen Yan, Danqing Hu, Jun Xu, Xian Zeng,
- Abstract summary: We propose TraceCoder, a framework integrating multi-source external knowledge to enhance traceability and explainability in ICD coding.<n>TraceCoder dynamically incorporates diverse knowledge sources, including UMLS, Wikipedia, and large language models (LLMs), to enrich code representations, bridge semantic gaps, and handle rare and ambiguous codes.<n>It also introduces a hybrid attention mechanism to model interactions among labels, clinical context, and knowledge, improving long-tail code recognition and making predictions interpretable by grounding them in external evidence.
- Score: 12.474362087939456
- License: http://creativecommons.org/licenses/by-nc-nd/4.0/
- Abstract: Automated International Classification of Diseases (ICD) coding assigns standardized diagnosis and procedure codes to clinical records, playing a critical role in healthcare systems. However, existing methods face challenges such as semantic gaps between clinical text and ICD codes, poor performance on rare and long-tail codes, and limited interpretability. To address these issues, we propose TraceCoder, a novel framework integrating multi-source external knowledge to enhance traceability and explainability in ICD coding. TraceCoder dynamically incorporates diverse knowledge sources, including UMLS, Wikipedia, and large language models (LLMs), to enrich code representations, bridge semantic gaps, and handle rare and ambiguous codes. It also introduces a hybrid attention mechanism to model interactions among labels, clinical context, and knowledge, improving long-tail code recognition and making predictions interpretable by grounding them in external evidence. Experiments on MIMIC-III-ICD9, MIMIC-IV-ICD9, and MIMIC-IV-ICD10 datasets demonstrate that TraceCoder achieves state-of-the-art performance, with ablation studies validating the effectiveness of its components. TraceCoder offers a scalable and robust solution for automated ICD coding, aligning with clinical needs for accuracy, interpretability, and reliability.
Related papers
- MedDCR: Learning to Design Agentic Workflows for Medical Coding [55.51674334874892]
Medical coding converts free-text clinical notes into standardized diagnostic and procedural codes.<n>We present MedDCR, a closed-loop framework that treats design as a learning problem.<n>On benchmark datasets, MedDCR outperforms state-of-the-art baselines.
arXiv Detail & Related papers (2025-11-17T13:30:51Z) - Probability-Biased Attention over Directed Bipartite Graphs for Long-Tail ICD Coding [12.66839524860715]
We propose a learning method that models fine-grained co-occurrence relationships among codes.<n>Our method achieves state-of-the-art performance with particularly notable improvements in Macro-F1.
arXiv Detail & Related papers (2025-10-31T04:47:09Z) - RAD: Towards Trustworthy Retrieval-Augmented Multi-modal Clinical Diagnosis [56.373297358647655]
Retrieval-Augmented Diagnosis (RAD) is a novel framework that injects external knowledge into multimodal models directly on downstream tasks.<n>RAD operates through three key mechanisms: retrieval and refinement of disease-centered knowledge from multiple medical sources, a guideline-enhanced contrastive loss transformer, and a dual decoder.
arXiv Detail & Related papers (2025-09-24T10:36:14Z) - MKE-Coder: Multi-Axial Knowledge with Evidence Verification in ICD Coding for Chinese EMRs [9.615982382826768]
This paper introduces a novel framework called MKE-Coder: Multi-axial Knowledge with Evidence verification in ICD coding for Chinese EMRs.<n>We identify candidate codes for the diagnosis and categorize each of them into knowledge under four coding axes.<n>We retrieve corresponding clinical evidence from the comprehensive content of EMRs and filter credible evidence through a scoring model.
arXiv Detail & Related papers (2025-02-19T08:08:53Z) - Medchain: Bridging the Gap Between LLM Agents and Clinical Practice with Interactive Sequence [68.05876437208505]
We present MedChain, a dataset of 12,163 clinical cases that covers five key stages of clinical workflow.<n>We also propose MedChain-Agent, an AI system that integrates a feedback mechanism and a MCase-RAG module to learn from previous cases and adapt its responses.
arXiv Detail & Related papers (2024-12-02T15:25:02Z) - Unlocking Potential Binders: Multimodal Pretraining DEL-Fusion for Denoising DNA-Encoded Libraries [51.72836644350993]
Multimodal Pretraining DEL-Fusion model (MPDF)
We develop pretraining tasks applying contrastive objectives between different compound representations and their text descriptions.
We propose a novel DEL-fusion framework that amalgamates compound information at the atomic, submolecular, and molecular levels.
arXiv Detail & Related papers (2024-09-07T17:32:21Z) - Exploring LLM Multi-Agents for ICD Coding [15.730751450511333]
The proposed multi-agent method for ICD coding effectively mimics the real-world coding process and improves performance on both common and rare codes.
Our method achieves comparable results to state-of-the-art ICD coding methods that require extensive pre-training or fine-tuning, and outperforms them in rare code accuracy, and explainability.
arXiv Detail & Related papers (2024-04-01T15:17:39Z) - CoRelation: Boosting Automatic ICD Coding Through Contextualized Code
Relation Learning [56.782963838838036]
We propose a novel approach, a contextualized and flexible framework, to enhance the learning of ICD code representations.
Our approach employs a dependent learning paradigm that considers the context of clinical notes in modeling all possible code relations.
arXiv Detail & Related papers (2024-02-24T03:25:28Z) - TransICD: Transformer Based Code-wise Attention Model for Explainable
ICD Coding [5.273190477622007]
International Classification of Disease (ICD) coding procedure has been shown to be effective and crucial to the billing system in medical sector.
Currently, ICD codes are assigned to a clinical note manually which is likely to cause many errors.
In this project, we apply a transformer-based architecture to capture the interdependence among the tokens of a document and then use a code-wise attention mechanism to learn code-specific representations of the entire document.
arXiv Detail & Related papers (2021-03-28T05:34:32Z) - A Meta-embedding-based Ensemble Approach for ICD Coding Prediction [64.42386426730695]
International Classification of Diseases (ICD) are the de facto codes used globally for clinical coding.
These codes enable healthcare providers to claim reimbursement and facilitate efficient storage and retrieval of diagnostic information.
Our proposed approach enhances the performance of neural models by effectively training word vectors using routine medical data as well as external knowledge from scientific articles.
arXiv Detail & Related papers (2021-02-26T17:49:58Z) - Inheritance-guided Hierarchical Assignment for Clinical Automatic
Diagnosis [50.15205065710629]
Clinical diagnosis, which aims to assign diagnosis codes for a patient based on the clinical note, plays an essential role in clinical decision-making.
We propose a novel framework to combine the inheritance-guided hierarchical assignment and co-occurrence graph propagation for clinical automatic diagnosis.
arXiv Detail & Related papers (2021-01-27T13:16:51Z)
This list is automatically generated from the titles and abstracts of the papers in this site.
This site does not guarantee the quality of this site (including all information) and is not responsible for any consequences.