Automated cross-sectional view selection in CT angiography of aortic
dissections with uncertainty awareness and retrospective clinical annotations
- URL: http://arxiv.org/abs/2111.11269v1
- Date: Mon, 22 Nov 2021 15:11:36 GMT
- Title: Automated cross-sectional view selection in CT angiography of aortic
dissections with uncertainty awareness and retrospective clinical annotations
- Abstract summary: We show how manual annotations routinely collected in a clinic can be efficiently used to ease this task.
Ill-posed but repetitive imaging tasks can be eased or automated by leveraging imperfect, retrospective clinical annotations.
- Score: 11.415942647070796
- License: http://arxiv.org/licenses/nonexclusive-distrib/1.0/
- Abstract: Objective: Surveillance imaging of chronic aortic diseases, such as
dissections, relies on obtaining and comparing cross-sectional diameter
measurements at predefined aortic landmarks, over time. Due to a lack of robust
tools, the orientation of the cross-sectional planes is defined manually by
highly trained operators. We show how manual annotations routinely collected in
a clinic can be efficiently used to ease this task, despite the presence of a
non-negligible interoperator variability in the measurements.
Impact: Ill-posed but repetitive imaging tasks can be eased or automated by
leveraging imperfect, retrospective clinical annotations.
Methodology: In this work, we combine convolutional neural networks and
uncertainty quantification methods to predict the orientation of such
cross-sectional planes. We use clinical data randomly processed by 11 operators
for training, and test on a smaller set processed by 3 independent operators to
assess interoperator variability.
Results: Our analysis shows that manual selection of cross-sectional planes
is characterized by 95% limits of agreement (LOA) of $10.6^\circ$ and
$21.4^\circ$ per angle. Our method showed to decrease static error by
$3.57^\circ$ ($40.2$%) and $4.11^\circ$ ($32.8$%) against state of the art and
LOA by $5.4^\circ$ ($49.0$%) and $16.0^\circ$ ($74.6$%) against manual
processing.
Conclusion: This suggests that pre-existing annotations can be an inexpensive
resource in clinics to ease ill-posed and repetitive tasks like cross-section
extraction for surveillance of aortic dissections.
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